Oncogenic KRAS-mutant lung cancers remain treatment refractory.A better understanding of the shrimps is bugs shirt immune response of KRAS-mutant lung cancers is required to facilitate the development of potential therapeutic strategies.Regulatory T cells (Tregs) are a subset of immune cells that promote tumor progression through suppressing anti-t
Avian Influenza Virus PB1 Gene in H3N2 Viruses Evolved in Humans To Reduce Interferon Inhibition by Skewing Codon Usage toward Interferon-Altered tRNA Pools
ABSTRACT Influenza A viruses cause an annual contagious respiratory disease in humans and are responsible for periodic high-mortality human pandemics.Pandemic influenza A viruses usually result from the reassortment of gene segments between human and avian influenza viruses.These avian influenza virus gene segments need to adapt to humans.Here we f
Personality Predictors of Cyber-Victimization and Cyber-Bullying in Adolescence
The article presents an empirical study of personality predictors of cyber-victimization and cyber-bullying in adolescence.There is a shortage of domestic (Russian) studies of individual psychological predictors of both cyber victimization and cyber aggression.To overcome this deficit, an empirical study was organized on a sample of 220 students of
Reliability Approach to Optimal Thruster Configuration Design for Spacecraft Attitude Control Subsystem
An optimal thruster configuration for attitude control subsystem of a spacecraft is presented in this paper.The optimal configuration is designed according to minimum number of required thrusters for satisfying desired reliability with specific redundancy level.The genetic algorithm is employed for optimization process and feasibility of the result